Hi! I'm a third-year pharmacy student (not licensed yet!!! this is just for informational purposes!).
How long have you been taking these medications, and what are the doses? What dose of Trazodone are you taking, and what is it prescribed for? When starting these meds it does sadly get worse before it gets better, so it could possibly be your body just trying to adjust. So take your meds everyday!! therapeutic benefit will not be seen until around 6-8 weeks! While Sertraline and Trazodone both affect serotonin, low-dose Trazodone mainly targets histamine and alpha-1 receptors, making it act primarily as a sleep aid rather than an antidepressant. Because of this, pairing low-dose Trazodone for insomnia with an SSRI like Zoloft is very common.Additionally, Trazodone generally carries a significantly lower risk of sexual side effects compared to standard SSRIs because it blocks specific serotonin (5-HT2a) receptors, which helps alleviate some of the typical serotonergic sexual dysfunction.
I also did some research myself, as I did not go over this in class, as I will tell you what I know so far.
PSSD is a disorder that occurs LONG AFTER discontinuation of ALL drugs that are involved with the serotonin in the brain, typicially for at least 3 OR MORE MONTHS. to get this diagnosis, the doctor would have to rule out current medication use! Meaning, PSSD cannot be diagnosed while you are still actively taking your medications. What you might be experiencing are the side effects of the antidepressants, which do overlap a little, but the overall criteria is very distinct!
if you are genuinely concerned, i would consult your psychiatrist/doctor to see about maybe taking wellbutrin (but will possibly cause seizures,especially at high doses, so if you have epilepsy, a seizure disorder, head traumas, any CNS lesions, or eating disorders, DO NOT TAKE!!!)/viagra/mirtazepine (but I dont you specifically as I am a stranger so I dont know the specific medication you should take— PLEASE TALK TO YOUR DOCTOR/PSYCHIATRIST!), adjust the timing you take the medications, possibly reducing the dose, or switching the antidepressant(s)!
I am reiterating!! I am an UNLICENSED PHARMACY STUDENT, and a COMPLETE AND TOTAL STRANGER, so I am just giving you general information from classes and the DSM-5. SO I BEG PLEASE TALK TO A LICENSED HEALTH CARE PROFESSIONAL!! I hope this somewhat helps!!